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All mice were maintained under specific pathogen-free conditions under license and approval of local animal research ethics committee committee (Health Products Regulatory Authority [HPRA], Ireland) and European Union regulations

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Handling and Stability Risks Improper handling exposure to light, heat, repeated freeze-thaw cycles, or strongly alkaline conditions can degrade the peptide or disrupt copper coordination, producing experimental variability that is sometimes mistaken for biological inconsistency

Supporters suggest it may help reduce pain, improve tendon repair, and support a faster return to activity

it might be difficult for them to effectively cross the skin due to poor permeability 23